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iation Safety Officer Course Module 1.6 – Biological Effect of Radiations

PART 1
BASIC KNOWLEDGE

MODULE 1.6
BIOLOGICAL EFFECTS OF RADIATIONS

CONTENTS

OVERVIEW………………………………………………………………………..1
LEARNING OBJECTIVE…………………….………………………………….. 1
1. THE HUMAN BODY………………………………………………………….. 2

1.1 Respiratory system………………..…………………………….……..3
1.2 Digestive System………………..…………………………………….. 4
1.3 Circulatory System………………..……………………………….….. 5
1.4 Lymphatic System………………..………………………………….... 5
1.5 Urinary System………………..………………………………………..6
1.6 Summary of Body Systems………………..…………………….…… 6
SELF-CHECK 1………………..………………………………………………… 6
2. CELLS AND THE BIOLOGICAL DAMAGE FROM RADIATION…………7
2.1 Cell Structure………………..………………………………..……….. 7
2.2 Cell Division………………..……………………………….………….. 8
2.3 Radiation Damage………………..…………….…………………….. 8

2.3.1 Cell damage………………..…………………………………….. 9
2.3.2 Effects of cell damage……………..……………………..………9
2.3.3 Cell repair………………..………………………………………...10
SELF-CHECK 2………………..……………..………………………………….. 10
3. EFFECTS OF RADIATION ON HUMANS……………..…………………...11
3.1 Deterministic Effects……………..……………………..…………….. 11
3.2 Stochastic Effects……………..……………………..………………... 13
3.2.1 Hereditary effects……………..……………………..……………14
3.2.2 Tissue weighting factors…………..……………………..……… 15
3.3 Exposure of the Foetus……………………………………………….. 16
3.4 Summary of Radiation Effects……………………………………….. 16

SELF-CHECK 3 17

KEY POINTS 17

King Faisal Specialist Hospital and Research Centre – Biomedical Physics Department i
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